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Concept information

Preferred term

calprotectin  

Definition(s)

  • Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation. (Wikipedia)

Broader concept(s)

Synonym(s)

  • 27e10 antigen
  • antigen, 27e10
  • antigen, l1
  • antigen l1, myelomonocytic
  • calcium binding myeloid protein p8,14
  • calcium-binding myeloid protein p8,14
  • calgranulin
  • l1 antigen
  • l1 protein, leukocyte
  • leukocyte l1 antigen complex
  • leukocyte l1 protein
  • migratory inhibitory factor related protein mrp
  • migratory inhibitory factor-related protein mrp
  • myelomonocytic antigen l1

Creator

  • Patricia Fener

In other languages

  • French

  • antigène 27E10
  • antigène L1
  • calgranuline
  • complexe antigénique L1 leucocytaire
  • protéine L1 leucocytaire
  • protéine MRP8/14

URI

http://data.loterre.fr/ark:/67375/C0X-ZKKZN16B-8

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